30
Participants
Start Date
October 1, 2016
Primary Completion Date
December 31, 2020
Study Completion Date
December 31, 2020
Biomarkers
Evaluate the intracellular and intraluminal distribution of autophagy and calcium efflux markers in each breast lesion in comparison to the HER2, proliferation (Ki-67, PCNA), p53, inflammatory, and apoptotic (Annexin-1) markers in the same patient. Determine the qualitative amount and localization of PMCA2 and Vitamin D Receptor in each breast lesion with intraductal calcium spicules compared to lesions without microcalcifications.
Sentara Surgery Specialists and Dorothy G Hoefer Comprehensive Breast Center, Newport News
George Mason University
OTHER
Dorothy G. Hoefer Foundation
OTHER
Sentara Norfolk General Hospital
OTHER