NCT03147560 - Immunogenicity and Safety Evaluation of Different Sequential Immunization Strategies by Sabin IPV and bOPV in Chinese Infants | Biotech Hunter

Enrollment

528

Participants

Timeline

Start Date

May 2, 2017

Primary Completion Date

December 30, 2017

Study Completion Date

December 30, 2017

Conditions

Polio

Interventions

BIOLOGICAL

Sabin IPV+ bOPV+ bOPV

Give 3 doses of polio vaccine at 2, 3 and 4 months of age, get 2 blood samples (1.5ml per sample) before the first dose and 28-35 days after the last dose. sIPV was given 0.5ml per dose and bOPV was given 0.1ml per dose.

BIOLOGICAL

Sabin IPV + Sabin IPV + bOPV

Give 3 doses of polio vaccine at 2, 3 and 4 months of age, get 2 blood samples (1.5ml per sample) before the first dose and 28-35 days after the last dose. sIPV was given 0.5ml per dose and bOPV was given 0.1ml per dose.

BIOLOGICAL

Sabin IPV + Sabin IPV + Sabin IPV

Give 3 doses of polio vaccine at 2, 3 and 4 months of age, get 2 blood samples (1.5ml per sample) before the first dose and 28-35 days after the last dose. sIPV was given 0.5ml per dose and bOPV was given 0.1ml per dose.

Trial Locations (2)

Unknown

Chunan Center for Disease Control and Prevention, Hangzhou

Longyou Center for Disease Control and Prevention, Quzhou