5,920
Participants
Start Date
April 17, 2017
Primary Completion Date
March 31, 2020
Study Completion Date
March 31, 2020
RABIPUR®
Year 1 (2017) Three doses of rabies vaccine (April, May, June) Year 2 and 3 (2018/19) One dose of Hepatitis A vaccine (June)
RTS,S/AS01
Year 1 (2017) Three doses of RTSS/AS01 (April, May, June) Year 2 and 3 (2018/19) One booster dose of RTSS/AS01 (June)
SMC with SP+AQ
Year 1, 2 and 3(2017/18/19) Four cycles of SMC (SP+AQ) during the malaria transmission season One cycle of SMC for children above one year of age consisting of sulphadoxine - pyrimethamin (SP) 500mg/25 mg, and amodiaquine (AQ) 150mg on day 1, and AQ 150mg on days 2 and 3. Infants will receive half of these doses.
SMC placebo
Year 1, 2 and 3(2017/18/19) Four cycles of SMC placebo during the malaria transmission season
Institut de Recherche en Sciences de la Santé, Direction Régionale de l'Ouest, Ouagadougou
Malaria Research & Training Center, Bamako
Malaria Research and Training Center, Bamako, Mali
OTHER
Institut de Recherche en Sciences de la Sante, Burkina Faso
OTHER_GOV
London School of Hygiene and Tropical Medicine
OTHER