54
Participants
Start Date
September 18, 2017
Primary Completion Date
September 1, 2018
Study Completion Date
November 24, 2019
Rocuronium
Experimental: Sugammadex Participants to have cystoscopy with bladder tumor resection. Rocuronium used to induce the neuromuscular blockade and given in a rapid sequence for endotracheal intubation at a dose of 0.45 mg/kg of Ideal Body Weight. If maintenance is needed for continued relaxation then a dose of 0.15 mg/kg of Ideal Body Weight repeated as necessary.
Sugammadex
Sugammadex administered as a single bolus, intravenous injection. The amount used is based on the patient's weight. A dose of 4 mg/kg used if recovery has reached at least 1-2 post-tetanic counts (PTC) following Rocuronium induced blockade.
Neostigmine
70 mcg/kg by vein to reverse the muscle relaxation.
Glycopyrrolate
14 mcg/kg by vein to reverse the muscle relaxation.
University of Texas MD Anderson Cancer Center, Houston
Merck Sharp & Dohme LLC
INDUSTRY
M.D. Anderson Cancer Center
OTHER