130
Participants
Start Date
July 10, 2017
Primary Completion Date
March 20, 2019
Study Completion Date
June 20, 2019
LUS-guided strategy-of-care
"For patients randomized to the strategy-of-care arm, the LUS guided protocol will be initiated and continued until there is a decrease in B-lines to ≤ 15 or 6 hours of care has been delivered, whichever comes first.~Treatment protocol:~1. IV furosemide (unless already given): 2x single oral dose if on chronic therapy or 20-40 mg if diuretic naive.~2. Optional therapies: non-invasive ventilation, vasodilators (SL, topical, or IV)~3. Reassessment every 2 hours"
Usual Care
Patients will receive usual AHF care
Intravenous Loop Diuretic
IV loop diuretic
Vasodilator
IV, topical, or SL Vasodilator
Non invasive Ventilation (NIV)
Face, mouth, or nasal mask applied to provide positive pressure ventilation
INOVA Health System, Fairfax
Vanderbilt University, Nashville
Case Western Reserve University, Cleveland
Eskenazi Health, Indianapolis
IU Health Methodist Hospital, Indianapolis
Detroit Receiving Hospital, Detroit
Inova Fairfax Hospital
OTHER
Vanderbilt University
OTHER
Case Western Reserve University
OTHER
Wayne State University
OTHER
Indiana University
OTHER