High-voltage Pulsed Radiofrequency on Gasserian Ganglion to Treat Patients With Primary Trigeminal Neuralgia

NACompletedINTERVENTIONAL
Enrollment

134

Participants

Timeline

Start Date

April 28, 2017

Primary Completion Date

September 3, 2020

Study Completion Date

September 3, 2021

Conditions
Idiopathic Trigeminal Neuralgia
Interventions
DEVICE

High-voltage pulsed radiofrequency

The manual PRF mode of the pain treatment generator will be turned on, the upper temperature limit will be set at 42°C, the PRF output voltage will be gradually increased to the highest voltage the patient can tolerate, and the patient will be treated for 360 s. After the treatment, 1.4 ml of a mixture of 0.4 mL of normal saline and 1 mL of 1% plain lidocaine will be injected through the needle of the cannula, and before the needle being removed, 0.5 mL of normal saline will be injected.

DRUG

Nerve block

The radiofrequency generator will be set at the sensory stimulating mode, and the lowest frequency of 0.2 V will be used for 360s-sham PRF treatment, after which 1.4 mL of a mixture of 2 mg of dexamethasone sodium phosphate and 1 mL of 1% plain lidocaine will be slowly injected through the radiofrequency treatment cannula needle. Before the needle being removed, 0.5 mL of normal saline will be injected.

Trial Locations (3)

100015

Beijing Ditan Hospital, Beijing

100050

Beijing Friendship Hospital, Beijing

Beijing Tiantan Hospital, Beijing

All Listed Sponsors
collaborator

Beijing Friendship Hospital

OTHER

collaborator

Beijing Ditan Hospital

OTHER

lead

Beijing Tiantan Hospital

OTHER

NCT03131466 - High-voltage Pulsed Radiofrequency on Gasserian Ganglion to Treat Patients With Primary Trigeminal Neuralgia | Biotech Hunter | Biotech Hunter