The Danish Non-vitamin K Antagonist Oral Anticoagulation Study in Patients With Venous Thromboembolism (DANNOAC-VTE)

PHASE4Active, not recruitingINTERVENTIONAL
Enrollment

5,000

Participants

Timeline

Start Date

April 1, 2023

Primary Completion Date

March 31, 2027

Study Completion Date

March 31, 2029

Conditions
Deep Vein ThrombosisPulmonary Embolism
Interventions
DRUG

Dabigatran Etexilate Oral Capsule

After cluster randomization, the cluster will use dabigatran to all their patients with venous thromboembolism when possible for six months. Hereafter the cluster will use the other three NOACs for six months one at the time. It is the clusters and not the patient that are randomized.

DRUG

Rivaroxaban Oral Tablet

After cluster randomization, the cluster will use rivaroxaban to all their patients with venous thromboembolism when possible for six months. Hereafter the cluster will use the other three NOACs for six months one at the time. It is the clusters and not the patient that are randomized.

DRUG

Edoxaban Oral Tablet

After cluster randomization, the cluster will use edoxaban to all their patients with venous thromboembolism when possible for six months. Hereafter the cluster will use the other three NOACs for six months one at the time. It is the clusters and not the patient that are randomized.

DRUG

Apixaban Oral Tablet

After cluster randomization, the cluster will use apixaban to all their patients with venous thromboembolism when possible for six months. Hereafter the cluster will use the other three NOACs for six months one at the time. It is the clusters and not the patient that are randomized.

Trial Locations (26)

2100

Rigshospitalet, Copenhagen Ø

2300

Amager Hospital, Copenhagen S

2400

Bispebjerg and Frederiksberg Hospital, Copenhagen

Bispebjerg Hospital, Copenhagen NV

2600

Glostrup Hospital - Department of Emergency Medicine, Glostrup Municipality

Glostrup Hospital - Department of Medicine / Cardiology, Glostrup Municipality

Glostrup Hospital - Department of Neurology, Glostrup Municipality

2650

Hvidovre Hospital, Hvidovre

2730

Herlev-Gentofte Hospital - Department of Medicine, Herlev

2900

Herlev Gentofte Hospital, Gentofte Municipality

3400

Nordsjællands Hospital - Hillerød, Hillerød

3600

Nordsjællands Hospital - Frederiksund, Frederikssund

3700

Bornhoms Hospital, Rønne

4000

Zealand University Hospital - Department of Neurology, Roskilde

Zealand University Hospital Roskilde - Department of Cardiology, Roskilde

4200

Slagelse Hospital, Slagelse

4300

Holbæk Hospital, Holbæk

4700

Næstved Hospital, Næstved

5000

Odense University Hospital - Department of Cardiology, Odense

Odense University Hospital - Department of Emergency Medicine, Odense

Odense University Hospital - Department of Geriatrics, Odense

5700

Odense University Hospital Svendborg, Svendborg

6700

Esbjerg Hospital, Esbjerg

7100

Vejle Hospital, Vejle

8200

Aarhus University Hospital, Aarhus

9800

Hjørring Hospital, Hjørring

All Listed Sponsors
lead

Herlev and Gentofte Hospital

OTHER