Sperm DNA Damage to Intracytoplasmic Sperm Injection Outcome

CompletedOBSERVATIONAL
Enrollment

120

Participants

Timeline

Start Date

April 1, 2018

Primary Completion Date

September 15, 2019

Study Completion Date

October 30, 2019

Conditions
Infertility, Male
Interventions
DIAGNOSTIC_TEST

Sperm DNA integrity by flow cytometry

flowcytometric test where sperm DNA breaks are evaluated indirectly through the DNA denaturability. The assay measures the susceptibility of sperm DNA to acid-induced DNA denaturation in situ, followed by staining with the fluorescence dye acridine orange. By using a flow cytometer 5.000-10.000 sperm can be analyzed within few seconds and thus provide a less subjective result compared to the World health organization analysis where only 1-300 cells are analyzed.

Trial Locations (1)

002

Ahmed Abbas, Assiut

All Listed Sponsors
lead

Assiut University

OTHER

NCT03129243 - Sperm DNA Damage to Intracytoplasmic Sperm Injection Outcome | Biotech Hunter | Biotech Hunter