Trauma Induced Coagulopathy and Inflammation

CompletedOBSERVATIONAL
Enrollment

300

Participants

Timeline

Start Date

February 27, 2017

Primary Completion Date

December 31, 2020

Study Completion Date

December 31, 2020

Conditions
Trauma InjuryTraumaCoagulopathy
Interventions
DIAGNOSTIC_TEST

Thromboelastography

Thromboelastography (TEG) tests for parameters related to efficiency of blood coagulation. The parameters are: reaction time (R value), the K value, the angle and the maximum amplitude (MA)

DIAGNOSTIC_TEST

Computational model

The computational whole-patient systems model is a multiscale, multi-compartment model whose state-space is defined by a very large and heterogeneous set of variables as well as a large number of input parameters. The model will be integrated in time for various initial trauma conditions in an attempt to determine whether the model can be predictive, and help us discover new variables that are more predictive of clinical outcomes than those employed in current clinical protocols.

Trial Locations (1)

19104

Penn Presbyterian Medical Center, Philadelphia

All Listed Sponsors
collaborator

Princeton University

OTHER

lead

University of Pennsylvania

OTHER

NCT03128658 - Trauma Induced Coagulopathy and Inflammation | Biotech Hunter | Biotech Hunter