Endothelial Function in Obstructive Sleep Apnea

EARLY_PHASE1CompletedINTERVENTIONAL
Enrollment

106

Participants

Timeline

Start Date

September 1, 2017

Primary Completion Date

January 30, 2020

Study Completion Date

May 7, 2021

Conditions
Obstructive Sleep Apnea of Adult
Interventions
DRUG

Atorvastatin 10mg

Atorvastatin 10 mg daily for 28 days will be randomly allocated to OSA patients regardless of adherence with CPAP. CPAP is a standard of care for OSA and will be prescribed by care providers not associated with this study based on clinical indications. The investigators will have no role in prescribing CPAP. Atorvastatin and placebo will be encapsulated to appear identical and dispensed by the research pharmacy.

DRUG

Placebo

Placebo daily for 28 days will be randomly allocated to OSA patients regardless of adherence with CPAP. CPAP is a standard of care for OSA and will be prescribed by care providers not associated with this study based on clinical indications. The investigators will have no role in prescribing CPAP. Atorvastatin and placebo will be encapsulated to appear identical and dispensed by the research pharmacy.

Trial Locations (1)

10032

Columbia University Medical Center, New York

All Listed Sponsors
collaborator

National Heart, Lung, and Blood Institute (NHLBI)

NIH

lead

Columbia University

OTHER

NCT03122639 - Endothelial Function in Obstructive Sleep Apnea | Biotech Hunter | Biotech Hunter