Fluid Restriction in Respiratory Distress of the Newborn

NACompletedINTERVENTIONAL
Enrollment

65

Participants

Timeline

Start Date

March 1, 2017

Primary Completion Date

July 24, 2020

Study Completion Date

March 31, 2021

Conditions
Respiratory Distress Syndrome, Newborn
Interventions
OTHER

Fluid Management Intervention

Fluid management intervention is fluid restriction to 60 mL/kg/day on Day of Life (DOL) 1 for preterm and 40 mL/kg/day on DOL 1 for term neonates, calculated as total of IV and enteral fluid intake. Infants randomized to low infusion with be placed on 10% dextrose and the Infant will be monitored by obtaining serum glucose levels by point of care testing. Glucose infusion rates (GIR) would be calculated to the corresponding serum glucose and recorded. After 24 hours, infusion rate will be increased to 60ml/kg/d providing minimum GIR \>4mg/kg/d. . Total fluid intake will be increased by 20 mL/kg/day until 150 mL/kg/day .

Trial Locations (2)

73501

Comanche county Memorial hospital, Lawton

10029-5674

Icahn School of Medicine at Mount Sinai, New York

All Listed Sponsors
collaborator

Icahn School of Medicine at Mount Sinai

OTHER

collaborator

Universidad Abierta Interamericana

OTHER

lead

University of Oklahoma

OTHER

NCT03120585 - Fluid Restriction in Respiratory Distress of the Newborn | Biotech Hunter | Biotech Hunter