Long Protocol and Freeze All Embryos vs Antagonist Protocol With Fresh Embryo Transfer in PCOS Patients Undergoing ICSI

PHASE4CompletedINTERVENTIONAL
Enrollment

204

Participants

Timeline

Start Date

April 21, 2017

Primary Completion Date

November 1, 2017

Study Completion Date

November 3, 2017

Conditions
Invitro Fertilization
Interventions
DRUG

Triptorelin

daily SC injection of Triptorelin 0.1 mg started at day 21 of the cycle prior to stimulation cycle and continued till the day of hCG triggering.

DRUG

cetrorelix

Flexible GnRH antagonist protocol was done with daily s.c administration of cetrorelix 0.25 mg started when one or more of the following criteria were achieved: (i) one or more follicle reached 14 mm diameter; (ii) The level of serum E2 reached 600 pg/ml; and (iii) The level of serum LH levels reached 10 IU/l .

DRUG

Recombinant Follicle Stimulating Hormone

Daily sc rFSH (Gonal-f; Merck Serono , Darmstadt, Germany) injections was started on 2nd day of the cycle in the antagonist protocol. Continuation of rFSH and GnRH antagonist daily until triggering day was done.

Trial Locations (1)

12151

Ahmed Maged, Cairo

All Listed Sponsors
lead

Cairo University

OTHER

NCT03118830 - Long Protocol and Freeze All Embryos vs Antagonist Protocol With Fresh Embryo Transfer in PCOS Patients Undergoing ICSI | Biotech Hunter | Biotech Hunter