Saturation Targets and Resuscitation in Preterm Trial

NACompletedINTERVENTIONAL
Enrollment

75

Participants

Timeline

Start Date

September 20, 2017

Primary Completion Date

September 30, 2019

Study Completion Date

September 30, 2022

Conditions
Oxidative Stress
Interventions
OTHER

Titration of oxygen during neonatal resuscitation

Resuscitation will be initiated at 30% O2 and target goal saturations will be the 10th to 25th percentile saturations in OX25 and 75th percentile in OX75 group. The control group will be resuscitated with the OX50 strategy in which resuscitation will be initiated with 30% O2 and target goal saturations will be the approximated median SpO2 observed in healthy term newborns as per current NRP guidelines. For the first 6 minutes after birth, target ranges of of all 3 arms are different. After 6 min, the target ranges are are identical.

Trial Locations (1)

75039

Parkland Hospital, Dallas

All Listed Sponsors
collaborator

American Academy of Pediatrics

OTHER

collaborator

Eunice Kennedy Shriver National Institute of Child Health and Human Development (NICHD)

NIH

lead

University of Texas Southwestern Medical Center

OTHER

NCT03115463 - Saturation Targets and Resuscitation in Preterm Trial | Biotech Hunter | Biotech Hunter