General Anesthesia Versus Spinal Anesthesia in Patients of HELLP Syndrome

NACompletedINTERVENTIONAL
Enrollment

60

Participants

Timeline

Start Date

April 15, 2017

Primary Completion Date

December 1, 2017

Study Completion Date

January 1, 2018

Conditions
HELLP Syndrome
Interventions
PROCEDURE

Spinal Anesthesia

Spinal needle 25G with Quincke's bevel will be used. It will be induced with a total of 10 mg of 0.5% hyperbaric bupivacaine and 20 mcg fentanyl (total volume 2.4 ml) at the L3-4 interspace. The parturient will be returned to the supine position with a left lateral tilt of 15° to facilitate left uterine displacement. The upper sensory block level will be checked 5 min after the spinal injection by assessing the loss of cold sensation from alcohol swabs, to ensure that a Th6 sensory block level has been achieved.

PROCEDURE

General Anesthesia

Pre-oxygenation with oxygen 100% via a tight fitting mask rapid sequence technique. Induction is by thiopental (5 mg kg lean body weight) and succinylcholine1.5 mg kg body weight), cricoid pressure should be applied before consciousness is lost and kept in place until confirmation of tracheal intubation with capnography and the cuff of the tracheal tube is inflated. Auscultating the chest helps exclude endobronchial intubation. At this point, surgery may commence.

Trial Locations (1)

71516

Assiut university hospital, Faculty of medicine, Asyut

All Listed Sponsors
lead

Assiut University

OTHER

NCT03111446 - General Anesthesia Versus Spinal Anesthesia in Patients of HELLP Syndrome | Biotech Hunter | Biotech Hunter