A Phase 2 Multicenter Study of Axicabtagene Ciloleucel in Subjects With Relapsed/Refractory Indolent Non-Hodgkin Lymphoma

PHASE2CompletedINTERVENTIONAL
Enrollment

159

Participants

Timeline

Start Date

June 20, 2017

Primary Completion Date

December 5, 2024

Study Completion Date

December 5, 2024

Conditions
Follicular LymphomaMarginal Zone LymphomaIndolent Non-Hodgkin Lymphoma
Interventions
BIOLOGICAL

axicabtagene ciloleucel

A single infusion of axicabtagene ciloleucel CAR transduced autologous T cells administered intravenously.

DRUG

Cyclophosphamide

Administered intravenously

DRUG

Fludarabine

Administered intravenously

Trial Locations (19)

10032

Columbia University Medical Center, New York

14642

University of Rochester Medical Center (URMC), Rochester

15232

UPMC Hillman Cancer Center, Pittsburgh

19111

Fox Chase Cancer Center, Philadelphia

20007

Georgetown Lombardi Comprehensive Cancer Center, Washington D.C.

33136

University of Miami Hospital and Clinics, Miami

33612

H Lee Moffitt Cancer Center, Tampa

37203

Sarah Cannon Research Institute, Nashville

37232

Vanderbilt University Medical Center, Nashville

44106

Ohio State University Medical Center, Cleveland

59037

Centre Hospitalier Régional Universitaire de Lille, Lille

69495

Centre Hospitalier Lyon Sud, Pierre-Bénite

77030

MD Anderson Cancer Center, Houston

85234

Banner MD Anderson Cancer Center, Gilbert

90033

USC Norris Comprehensive Cancer Center, Los Angeles

90095

University of California Los Angeles, Los Angeles

98109

Fred Hutchinson Cancer Research Center, Seattle

02215

Dana Farber Cancer Institute, Boston

07601

Hackensack University Medical Center - John Theurer Cancer Center, Hackensack

All Listed Sponsors
lead

Kite, A Gilead Company

INDUSTRY

NCT03105336 - A Phase 2 Multicenter Study of Axicabtagene Ciloleucel in Subjects With Relapsed/Refractory Indolent Non-Hodgkin Lymphoma | Biotech Hunter | Biotech Hunter