The Effects of Individualized Oxygen Dynamic on Prognosis of Patients With High-risk Cardiac Surgery

NACompletedINTERVENTIONAL
Enrollment

286

Participants

Timeline

Start Date

March 5, 2017

Primary Completion Date

June 30, 2018

Study Completion Date

July 30, 2018

Conditions
Cardiac DiseaseHigh Risk Sex
Interventions
PROCEDURE

mean artery pressure

mean artery pressure declined with less than 20% of baseline

PROCEDURE

bispectral index

BIS 45-60 before and after CPB; and BIS 40-45 during CPB

PROCEDURE

Brain oxygen saturation

Brain oxygen saturation declined with less than 20% of baseline

OTHER

Controlled

receiving standard measures to achieve a heart rate (HR) in the range of 60-100 beats/min, central venous oxygen saturation (Svco2) higher than 70%, lactate level lower than 3 mmol/L, hematocrit value higher than 28%, and urinary output higher than 0.5 mL/kg/hr.

Trial Locations (1)

230022

The First Affiliated Hospital of Anhui Medical University, Hefei

All Listed Sponsors
lead

The First Affiliated Hospital of Anhui Medical University

OTHER

NCT03103633 - The Effects of Individualized Oxygen Dynamic on Prognosis of Patients With High-risk Cardiac Surgery | Biotech Hunter | Biotech Hunter