Neuromodulation of Lidocaine and Capsaicin Cream Effects on Pain Experience

NACompletedINTERVENTIONAL
Enrollment

103

Participants

Timeline

Start Date

May 31, 2016

Primary Completion Date

March 31, 2019

Study Completion Date

March 31, 2019

Conditions
Pain
Interventions
DEVICE

transcranial direct current stimulation (tDCS)

tCDS safely applies a weak electrical current to your scalp using two sponge electrodes that look like flat circular pads. The pads will be held in place on your head with a neoprene cap. The pads will be attached to a generator that will send a weak stimulus to your scalp. This current influences the way that your brain cells work. When the stimulus starts, you might feel a tingling sensation underneath the electrode pads. That sensation is not painful and goes away in seconds.

OTHER

Lidocaine cream

Lidocaine cream will be applied on the arm to reduce pain sensitivity (analgesia).

OTHER

Capsaicin cream

Capsaicin cream will be applied on the arm to increase pain sensitivity (hyperalgesia).

OTHER

Control cream

A neutral cream will be applied on the arm as a control.

Trial Locations (1)

02129

Massachusetts General Hospital, Charlestown

All Listed Sponsors
lead

Massachusetts General Hospital

OTHER

NCT03102710 - Neuromodulation of Lidocaine and Capsaicin Cream Effects on Pain Experience | Biotech Hunter | Biotech Hunter