NHFOV vs. NCPAP as a Primary Treatment to Neonatal Respiratory Distress Syndrome(NRDS)

NACompletedINTERVENTIONAL
Enrollment

340

Participants

Timeline

Start Date

April 27, 2017

Primary Completion Date

July 28, 2018

Study Completion Date

July 28, 2018

Conditions
Preterm Infants
Interventions
PROCEDURE

noninvasive high-frequency ventilation (nHFOV)

NHFOV will be provided by a high frequency ventilator (CNO, Medin, Germany or SLE 5000, UK). NHFOV will be provided via binasal prongs.

PROCEDURE

nasal continuous positive airway pressure (nCPAP)

Infants assigned to the NCPAP group will be started on a pressure of 6 cmH2O (range: 6-8 cmH2O) by CPAP system (CNO Medin, Germany, Carefusion, USA)

Trial Locations (1)

400000

Xingwang Zhu, Chongqing

All Listed Sponsors
collaborator

Guiyang Maternity and Child Health Care Hospital

OTHER

collaborator

Daping Hospital and the Research Institute of Surgery of the Third Military Medical University

OTHER

collaborator

Children's Hospital of Chongqing Medical University

OTHER

collaborator

Chongqing Maternal and Child Health Hospital

OTHER

collaborator

The Second Hospital of Shandong University

OTHER

collaborator

Yan'an Affiliated Hospital of Kunming Medical University

OTHER

collaborator

The Children's Hospital of Zhejiang University School of Medicine

OTHER

collaborator

Hunan Children's Hospital

OTHER_GOV

collaborator

Zhengzhou Children's Hospital, China

OTHER

collaborator

Chengdu Women's and Children's Central Hospital

OTHER

collaborator

The People's Hospital of Dehong Autonomous Prefecture

OTHER

collaborator

Kunming Children's Hospital

OTHER

collaborator

Chongqing Three Gorges Central Hospital

OTHER

collaborator

Shanxi Provincial Maternity and Children's Hospital

OTHER

collaborator

University of Southern California

OTHER

collaborator

Vilnius University

OTHER

collaborator

Children's Hospital of Fudan University

OTHER

collaborator

Guangdong Women and Children Hospital

OTHER

collaborator

Nanjing Children's Hospital

OTHER

lead

Xingwang Zhu

OTHER

NCT03099694 - NHFOV vs. NCPAP as a Primary Treatment to Neonatal Respiratory Distress Syndrome(NRDS) | Biotech Hunter | Biotech Hunter