"Therapeutic Hypothermia in Expanded Criteria Brain-dead Donors and Kidney-graft Function"

NACompletedINTERVENTIONAL
Enrollment

532

Participants

Timeline

Start Date

November 8, 2017

Primary Completion Date

March 21, 2022

Study Completion Date

March 21, 2022

Conditions
Organ DonorBrain DeathKidney Transplant; ComplicationsCritical IllnessHypothermia
Interventions
PROCEDURE

Procedure control: normothermia

Temperature will be maintained between 36.5° and 37.5°C in the control group. In case of temperature superior to 37.5°C or inferior to 36.5°C, a pharmaceutical treatment and/or active cooling or warming will be introduce to maintain temperature between the range of 36.5 - 37.5°C.

PROCEDURE

Procedure active

Therapeutic hypothermia ie targeted controlled temperature between 34° and 35°C will be induced in the active group. Usual method of controlled temperature will be used in ICU: internal active method or external active method.

Trial Locations (54)

13005

Hopital de la Conception, Marseille

Hopital de la Timone, Marseille

14000

CHU Caen, Caen

16959

CH Angouleme, Angoulême

17019

CH La Rochelle, La Rochelle

17108

CH Saintes, Saintes

18020

CH Bourges, Bourges

21079

CHU de Dijon, Dijon

22027

CH Saint Brieuc, Saint-Brieuc

28100

CH de Dreux, Dreux

29107

CH Cornouaille, Quimper

29200

CHU Brest, Brest

29672

CH Morlaix, Morlaix

31403

CHU Toulouse, Toulouse

33076

CHU de Bordeaux, Bordeaux

35000

CHU Rennes, Rennes

35403

CH Saint Malo, St-Malo

37044

CHU Tours, Tours

41016

CH de Blois, Blois

42055

CHRU Saint-Etienne, Saint-Etienne

44093

Nantes University Hospital, Nantes

44606

CH Saint Nazaire, Saint-Nazaire

45067

CH Orléans, Orléans

49000

CHU d'Angers, Angers

49325

Ch Cholet, Cholet

51100

CHU Reims, Reims

53000

CH Laval, Laval

54511

CHRU Nancy, Vandœuvre-lès-Nancy

56000

CH Vannes, Vannes

56322

CH Lorient, Lorient

59000

CHRU Lille, Lille

67091

CHU Strasbourg, Strasbourg

72037

CH Le Mans, Le Mans

74374

CH Annecy Genevois, Pringy

75010

Hopital Saint Louis, Paris

75013

Hopital de la Pitié Salpetriere, Paris

75015

Hopital Necker, Paris

75020

CHU Tenon, Paris

76000

CHU Rouen, Rouen

77600

CH Marne la Vallée (GHEF), Jossigny

80054

CHU Amiens-Picardie, Amiens

84000

CH Avignon, Avignon

85925

CH La Roche sur Yon, La Roche-sur-Yon

86000

CHU Poitiers, Poitiers

87042

CHU Limoges, Limoges

92150

CHU Foch, Suresnes

94000

Hopital Henri Mondor, Créteil

94270

Hopital Bicetre, Le Kremlin-Bicêtre

Unknown

Chu Clermont Ferrand, Clermont-Ferrand

CHU Grenoble, Grenoble

CHU de Lyon, Lyon

CH de Meaux (GHEF), Meaux

CHU Montpellier, Montpellier

06000

CHU Nice, Nice

All Listed Sponsors
collaborator

Ministry of Health, France

OTHER_GOV

lead

Nantes University Hospital

OTHER

NCT03098706 - "Therapeutic Hypothermia in Expanded Criteria Brain-dead Donors and Kidney-graft Function" | Biotech Hunter | Biotech Hunter