Low Tidal MEChanical Ventilation Against NO Ventilation During Cardiopulmonary Bypass Heart Surgery

NACompletedINTERVENTIONAL
Enrollment

1,502

Participants

Timeline

Start Date

May 2, 2017

Primary Completion Date

August 29, 2019

Study Completion Date

August 29, 2019

Conditions
Respiratory FailureAtelectasisPneumoniaPneumothoraxBleedingSurgery--ComplicationsCardiac Disease
Interventions
PROCEDURE

Low tidal volume ventilation (LTV arm)

During cardiopulmonary bypass, mechanical ventilation is maintained with settings described above.

PROCEDURE

No ventilation (noV arm)

During cardiopulmonary bypass, no mechanical ventilation is performed.

PROCEDURE

Lung recruitment manoeuver

"An insufflation with positive end-expiratory pressure +30 cmH20 during 5 seconds.~At the end of cardiopulmonary bypass, in the operative room. And after transfer to the ICU (intensive care unit)."

Trial Locations (1)

92200

CMC Ambroise Paré, Neuilly-sur-Seine

All Listed Sponsors
lead

CMC Ambroise Paré

OTHER

NCT03098524 - Low Tidal MEChanical Ventilation Against NO Ventilation During Cardiopulmonary Bypass Heart Surgery | Biotech Hunter | Biotech Hunter