Effect of Dexmedetomidine Combined With Low-dose Nalmefene on Preventing Remifentanil-induced Postoperative Hyperalgesia

NACompletedINTERVENTIONAL
Enrollment

150

Participants

Timeline

Start Date

February 6, 2017

Primary Completion Date

December 20, 2017

Study Completion Date

December 30, 2017

Conditions
PainAnesthesia
Interventions
DRUG

Normal saline

Normal saline is intravenously administrated before anesthesia induction

DRUG

Remifentanil

Remifentanil is intravenously administrated

DRUG

Sufentanil

Sufentanil is intravenously administrated

DRUG

Dexmedetomidine injection

Dexmedetomidine is intravenously administrated before anesthesia induction

DRUG

Nalmefene

Nalmefene is intravenously administrated before anesthesia induction

Trial Locations (1)

300052

Tianjin Medical University General Hospital, Tianjin

All Listed Sponsors
lead

Tianjin Medical University General Hospital

OTHER

NCT03096730 - Effect of Dexmedetomidine Combined With Low-dose Nalmefene on Preventing Remifentanil-induced Postoperative Hyperalgesia | Biotech Hunter | Biotech Hunter