Impact of Evolocumab on the Effects of Clopidogrel in Patients With High On-Treatment Platelet Reactivity

PHASE4CompletedINTERVENTIONAL
Enrollment

259

Participants

Timeline

Start Date

October 3, 2017

Primary Completion Date

November 2, 2020

Study Completion Date

November 2, 2020

Conditions
Atherosclerotic Cardiovascular Disease
Interventions
DRUG

Evolocumab

Patients will be randomly assigned to receive a single dose of either evolocumab 420 mg s.c. or placebo (0.9% sodium chloride s.c. injection).

OTHER

Placebo

Patients will be randomly assigned to receive a single dose of either evolocumab 420 mg s.c. or placebo (0.9% sodium chloride s.c. injection).

Trial Locations (1)

32209

University of Florida, Jacksonville

Sponsors

Collaborators (1)

All Listed Sponsors
collaborator

Amgen

INDUSTRY

lead

University of Florida

OTHER