Minimal Opioid Use After Total Hip Replacement (THR)

PHASE4CompletedINTERVENTIONAL
Enrollment

180

Participants

Timeline

Start Date

March 8, 2017

Primary Completion Date

June 28, 2019

Study Completion Date

September 27, 2019

Conditions
Osteoarthritis, Hip
Interventions
PROCEDURE

Periarticular injection (Deep injection)

"Deep injection of cocktail containing Bupivacaine with Epi, 30mL; Morphine, 8mg/mL, 1mL; Methyprednislone, 40mg/mL, 1mL; Cefazolin, 500mg in 10 mL; saline, 22mL into the anterior capsule, the periosteum, the gluteus maximus, and the abductor muscles and fascia lata."

PROCEDURE

Periarticular injection (Superficial injection)

Superficial injection of 40mL 0.25% Bupivacaine into subcutaneous tissue prior to wound closure.

DRUG

Bupivacaine

EPCA: Bupivacaine 0.06%.

DRUG

Placebo

EPCA: Saline.

Trial Locations (1)

10021

Hospital for Special Surgery, New York

All Listed Sponsors
lead

Hospital for Special Surgery, New York

OTHER

NCT03090152 - Minimal Opioid Use After Total Hip Replacement (THR) | Biotech Hunter | Biotech Hunter