Bovine Colostrum for Preterm Newborns

NACompletedINTERVENTIONAL
Enrollment

350

Participants

Timeline

Start Date

July 1, 2017

Primary Completion Date

October 23, 2020

Study Completion Date

November 18, 2020

Conditions
Enteral Feeding IntoleranceNecrotizing EnterocolitisLate-Onset Neonatal Sepsis
Interventions
DIETARY_SUPPLEMENT

Bovine Colostrum

Bovine colostrum (BC) is the first milk from cows after birth and we suggest that BC may be used to supplement MM, instead of infant formula or DM. BC is a rich source of protein (up to 150 g/L) and bioactive components, including lactoferrin, lysozyme, lactoperoxidase, immunoglobulins, and various growth factors, such as, IGF-I and -II, EGFs, and TGF-β. BC has repeatedly been shown to have beneficial effects in a well-established piglet model of preterm infants, using various feeding regimens, including a gradual regimen that would mimic enteral feeding for preterm infants without access to MM during the first week.

DIETARY_SUPPLEMENT

Preterm Formula

Preterm formula is a type of infant formula designed for preterm infants. It is used when mother's own milk is not available or not in sufficient amount as the enteral feeding for preterm infants in hospitals that do not have donor human milk.

Trial Locations (8)

Unknown

Dongguan Women and Children's Hospital, Dongguan

Foshan Maternal and Child Health Hospital, Foshan

The Sixth Affiliated Hospital of Sun Yat-sen University, Guangzhou

Longgang District Central Hospital of Shenzhen, Shenzhen

Shenzhen Luohu Maternal and Child Health Hospital, Shenzhen

Shenzhen Nanshan Maternal and Child Health Hospital, Shenzhen

Shenzhen People's Hospital, Shenzhen

University of Chinese Academy of Sciences-Shenzhen Hospital, Shenzhen

All Listed Sponsors
collaborator

Sixth Affiliated Hospital, Sun Yat-sen University

OTHER

collaborator

Maternal and Child Health Hospital of Foshan

OTHER

collaborator

Shenzhen People's Hospital

OTHER

collaborator

Shenzhen Luohu Maternal and Child Health Hospital

UNKNOWN

collaborator

University of Chinese Academy of Sciences - Shenzhen Hospital

UNKNOWN

collaborator

Longgang District People's Hospital of Shenzhen

OTHER

collaborator

Shenzhen Nanshan Maternity and Child Healthcare Hospital

UNKNOWN

collaborator

Dongguan Women and Children's Hospital

UNKNOWN

lead

Per Torp Sangild

OTHER

NCT03085277 - Bovine Colostrum for Preterm Newborns | Biotech Hunter | Biotech Hunter