Nutritional and Anti-infective Interventions for Malnutrition in Pregnancy (Beleuman Welbodi)

Specially formulated supplementary food for pregnancy

Standard of care for malnutrition in pregnancy in Sierra Leone

Sulfadoxine-pyrimethamine (500 mg / 25 mg) given every 4 weeks, beginning at enrollment or at 13 weeks' gestation, whichever is later.

Standard of care for Sierra Leone is 2 doses of sulfadoxine/ pyrimethamine (500mg/ 25mg).

An insecticide-treated mosquito net at the time of enrollment into the study.

Azithromycin 1 gram given once in second trimester and again during weeks 28-34 of gestation.

Single dose albendazole 400mg given in the second trimester.

Testing for bacterial vaginosis at enrollment and again at weeks 28-34 using a rapid diagnostic test for sialidase. Those with positive tests will receive extended release metronidazole 750mg daily for 7 days.