Rare Diseases Clinical Research Network: Neurophysiological Correlates

CompletedOBSERVATIONAL
Enrollment

185

Participants

Timeline

Start Date

January 2, 2017

Primary Completion Date

July 31, 2021

Study Completion Date

July 31, 2021

Conditions
Rett Syndrome, Preserved Speech VariantMecp2 Duplication SyndromeRett-related Disorders
Interventions
PROCEDURE

Auditory and Visual Event-related Potentials and EEG

Specifically, through up to three standardized sessions (i.e., annual \[every 10-14 months\]), we will assess AEP and VEP. ERP recordings will also provide data for specific rhythms/band (gamma and alpha) pattern analyses as secondary measures as well as technical control data, which will help to exclude those with co-current seizures.

Trial Locations (5)

37212

Vanderbilt University, Nashville

45229

Cincinnati Children's Hospital, Cincinnati

80045-2571

University of Colorado Denver, Denver

02115-5724

Boston Children's Hospital, Boston

19104-4318

Children's Hospital of Philadelphia, Philadelphia

All Listed Sponsors
collaborator

Children's Hospital of Philadelphia

OTHER

collaborator

University of Colorado, Denver

OTHER

collaborator

Boston Children's Hospital

OTHER

collaborator

Vanderbilt University

OTHER

collaborator

University of South Florida

OTHER

collaborator

International Rett Syndrome Foundation Rettsyndrome.org

UNKNOWN

collaborator

Eunice Kennedy Shriver National Institute of Child Health and Human Development (NICHD)

NIH

lead

University of Alabama at Birmingham

OTHER

NCT03077308 - Rare Diseases Clinical Research Network: Neurophysiological Correlates | Biotech Hunter | Biotech Hunter