NCT03075072View on ClinicalTrials.gov

Hippocampal Sparing Whole Brain Radiation Versus Stereotactic Radiation in Patients With 5-20 Brain Metastases: A Phase III, Randomized Trial

NAActive, not recruitingINTERVENTIONAL
Enrollment

196

Participants

Timeline

Start Date

April 10, 2017

Primary Completion Date

November 7, 2024

Study Completion Date

September 30, 2025

Conditions
Brain Metastases
Interventions
RADIATION

Whole brain radiation

Treatment of the whole brain with radiation. When possible the hippocampus will be spared from radiation.

RADIATION

Stereotactic radiation (SRS)

Focused radiation to each individual brain metastasis without treatment of the remainder of the brain.

Trial Locations (2)

02115

Brigham and Women's Hospital, Boston

02116

Dana Farber Cancer Institute, Boston

All Listed Sponsors
collaborator

Brigham and Women's Hospital

OTHER

lead

Dana-Farber Cancer Institute

OTHER

NCT03075072 - Hippocampal Sparing Whole Brain Radiation Versus Stereotactic Radiation in Patients With 5-20 Brain Metastases: A Phase III, Randomized Trial | Biotech Hunter | Biotech Hunter