Nurse-Led, Symptom-Based Screening of Household Child Contacts of Tuberculosis Index Cases

NACompletedINTERVENTIONAL
Enrollment

4,054

Participants

Timeline

Start Date

October 1, 2015

Primary Completion Date

September 15, 2018

Study Completion Date

September 15, 2018

Conditions
Tuberculosis
Interventions
OTHER

Symptom -based Screening(Child Contacts)

"Aim 1: Determine the number of child contacts per adult index case of tuberculosis to assess quality of contact tracing.~Aim 2: Determine the percentage of child contacts initiated on IPT or antituberculous therapy (ATT) and compare between intervention (symptom-based, nurse-led initiation of IPT) vs control clinics (TST-based screening with referral to hospital, current standard of care).~Aim 3: Compare outcomes of children initiated on IPT between both groups including: completion of therapy, discontinuation due to side effects, lost to follow up, and adherence while on therapy."

OTHER

Clinical based Decisions

the child is symptomatic, they will be referred to the hospital for further evaluation of TB disease including both chest X-ray and testing of either sputum or swallowed sputum. If the child is asymptomatic, the TB nurse at the local clinic will initiate them on weight-appropriate dosing of IPT

Trial Locations (1)

Unknown

PHRU, Klerksdorp

All Listed Sponsors
collaborator

United States Agency for International Development (USAID)

FED

lead

Johns Hopkins University

OTHER

NCT03074799 - Nurse-Led, Symptom-Based Screening of Household Child Contacts of Tuberculosis Index Cases | Biotech Hunter | Biotech Hunter