The Effect of Paravertebral Block With Dexamethasone on Intraoperative and Postoperative Analgesia in Children Undergoing Surgery for Coarctation of Aorta

PHASE1CompletedINTERVENTIONAL
Enrollment

50

Participants

Timeline

Start Date

October 30, 2016

Primary Completion Date

March 30, 2017

Study Completion Date

April 15, 2017

Conditions
Coarctation of Aorta
Interventions
DRUG

Dexamethasone

"Dexamethasone is commonly used in the perioperative period to reduce postoperative nausea and vomiting. Additionally, it has been reported to have analgesic effects.~The analgesic effect of epidural or perineural dexamethasone administration is not clear. Dexamethasone might have a local anesthetic effect on nerve by direct membrane action"

DEVICE

ultrasound

The growth of ultrasound technology and, with it, our ability to visualize the pleura and other structures in and around the paravertebral space has fueled a tremendous increased interest in performing thoracic paravertebral blocks. These blocks may be used for acute pain control, as an adjunct to general anesthesia for peri-operative pain control and, in some practices, as the primary anesthetic

PROCEDURE

paravertebral block

paravertebral block is an effective analgesic technique used in various types of surgery, trauma and chronic pain. it decreases postoperative pain and reduces opioid consumption which in turns improve postoperative pulmonary function hoping for early extubation.

DRUG

Bupivacaine

it is an amino amide local anesthetic drug

OTHER

isotonic saline

sterile sodium chloride solution at physiological concentration (0.87%); used as diluting agent when added to local anesthetic drug

Trial Locations (1)

02

Amany Hassan Saleh, Cairo

All Listed Sponsors
lead

Cairo University

OTHER

NCT03074773 - The Effect of Paravertebral Block With Dexamethasone on Intraoperative and Postoperative Analgesia in Children Undergoing Surgery for Coarctation of Aorta | Biotech Hunter | Biotech Hunter