Discontinuation of Disease Modifying Therapies (DMTs) in Multiple Sclerosis (MS)

PHASE4CompletedINTERVENTIONAL
Enrollment

259

Participants

Timeline

Start Date

April 20, 2017

Primary Completion Date

August 31, 2021

Study Completion Date

August 31, 2021

Conditions
Multiple Sclerosis
Interventions
DRUG

Discontinuation of disease modifying therapy

Participants who will discontinue their current MS drug. No other changes to their treatment occur.

DRUG

Standard of Care

Participants who remain on their current Disease Modifying Therapies (DMTs) without any changes. DMTs include \~14 formulations/doses of drugs approved in the US by the FDA that alter the natural history of the disease.

Trial Locations (19)

10016

NYU Langone Medical Center, New York

10029

Mt. Sinai University, New York

14642

University of Rochester, Rochester

15213

University of Pittsburgh, Pittsburgh

19104

University of Pennsylvania, Philadelphia

19107

Thomas Jefferson University, Philadelphia

20007

Georgetown University, Washington D.C.

22908

University of Virginia, Charlottesville

33136

University of Miami, Miami

37215

Vanderbilt University, Nashville

43221

The Ohio State University, Columbus

44195

Cleveland Clinic, Cleveland

63139

Washington University St. Louis, St Louis

66103

University of Kansas Medical Center, Kansas City

80045

University of Colorado Denver - Anschutz Medical Campus, Aurora

90033

University of Southern California, Los Angeles

97239

Oregon Health and Science University, Portland

98122

Swedish Health Services, Seattle

02114

Massachusetts General Hospital, Boston

All Listed Sponsors
collaborator

Patient-Centered Outcomes Research Institute

OTHER

collaborator

National Multiple Sclerosis Society

OTHER

collaborator

University of Alabama at Birmingham

OTHER

lead

University of Colorado, Denver

OTHER

NCT03073603 - Discontinuation of Disease Modifying Therapies (DMTs) in Multiple Sclerosis (MS) | Biotech Hunter | Biotech Hunter