Spironolactone With Patiromer in the Treatment of Resistant Hypertension in Chronic Kidney Disease

PHASE2CompletedINTERVENTIONAL
Enrollment

295

Participants

Timeline

Start Date

January 23, 2017

Primary Completion Date

November 27, 2018

Study Completion Date

November 27, 2018

Conditions
HyperkalemiaResistant Hypertension
Interventions
DRUG

Patiromer

2 packets/day starting dose, administered orally

DRUG

Placebo

2 packets/day starting dose, administered orally

DRUG

Spironolactone

25 mg tablet/day starting dose, administered orally

Trial Locations (40)

1612

Investigator Site 1402, Sofia

4032

Investigator Site 4611, Debrecen

10000

Investiagor Site 2205, Zagreb

Investigator Site 2201, Zagreb

Investigator Site 2202, Zagreb

Investigator Site 2203, Zagreb

33014

Investigator Site 1023, Miami Lakes

33021

Investigator Site 1012, Hollywood

37075

Investigator Site 4202, Göttingen

60611

Investigator Site 1022, Chicago

61002

Investiagor Site 7809, Kharkiv

61006

Investigator Site 7803, Kharkiv

61039

Investigator Site 7808, Kharkiv

61103

Investigator Site 7802, Kharkiv

69001

Investigator Site 7804, Zaporizhzhia

69118

Investigator Site 7807, Zaporizhzhia

0102

Investigator Site 3806, Tbilisi

0112

Investigator Site 3811, Tbilisi

0144

Investigator Site 3802, Tbilisi

0159

Investigator Site 3801, Tbilisi

Investigator Site 3804, Tbilisi

Investigator Site 3805, Tbilisi

Investigator Site 3807, Tbilisi

Investigator Site 3808, Tbilisi

Investigator Site 3810, Tbilisi

Investigator Site 3812, Tbilisi

Investigator Site 3813, Tbilisi

0186

Investigator Site 3809, Tbilisi

H-8230

Investigator Site 4607, Balatonfüred

H-1097

Investigator Site 4606, Budapest

H-3000

Investigator Site 4601, Hatvan

H-2143

Investigator Site 4605, Kistarcsa

H-3529

Investigator Site 4602, Miskolc

H-3530

Investigator Site 4610, Miskolc

H-9200

Investigator Site 4608, Mosonmagyaróvár

Unknown

Investigator Site 7403, Johannesburg

03680

Investigator Site 7805, Kiev

04114

Investigator Site 7801, Kiev

LE5 4QF

Investigator Site 8202, Leicester

Se5 9RS

Investigator Site 8205, London

All Listed Sponsors
lead

Relypsa, Inc.

INDUSTRY

NCT03071263 - Spironolactone With Patiromer in the Treatment of Resistant Hypertension in Chronic Kidney Disease | Biotech Hunter | Biotech Hunter