Investigation of Dental Health in Children With Neutrophil Defects: A Clinical Study

NACompletedINTERVENTIONAL
Enrollment

50

Participants

Timeline

Start Date

December 31, 2016

Primary Completion Date

December 31, 2018

Study Completion Date

December 31, 2019

Conditions
Primary Immune Deficiency DisorderPeriodontitis
Interventions
PROCEDURE

Oral hygiene advice, non surgical periodontal treatment

For children affected by periodontal disease, oral hygiene advice, non surgical periodontal treatment will also be performed according to needs. This can be accompanied, when appropriate, by the use of local anaesthesia and adjunctive antimicrobials (systemic or locally applied subgingivally), according to the clinical presentation and the child's medical conditions. Accurate supra- and sub-gingival removal of calculus and dental plaque will be performed both with ultrasonic and/or manual instruments. The necessary sub-gingival debridement will be performed in 1 to 4 visits (either full mouth treatment, half-mouth treatment or quadrant-wise treatment) depending on patient preference and practical considerations, using manual (Gracey curettes, Hu-Friedy) and ultrasonic devices (EMS). .

Trial Locations (2)

E1 2AD

Center for Oral Clinical Research, Queen Mary, University of London, London

WC1N 3JH

Dental and Maxillofacial Department, Great Ormond Street Hospital for Children, London

All Listed Sponsors
collaborator

Great Ormond Street Hospital for Children NHS Foundation Trust

OTHER

lead

Queen Mary University of London

OTHER

NCT03069079 - Investigation of Dental Health in Children With Neutrophil Defects: A Clinical Study | Biotech Hunter | Biotech Hunter