Mifepristone and Misoprostol Versus Misoprostol Alone in the Medical Management of Missed Miscarriage

PHASE3CompletedINTERVENTIONAL
Enrollment

711

Participants

Timeline

Start Date

September 20, 2017

Primary Completion Date

January 9, 2020

Study Completion Date

January 9, 2020

Conditions
Missed Miscarriage
Interventions
DRUG

Mifepristone, Oral, 200 Mg

The Investigational Medicinal Product (IMP) is a single dose of 200mg mifepristone to be taken orally after confirmation of missed miscarriage by pelvic ultrasound scan.

DRUG

Placebo Oral Tablet

The placebo will be an oral tablet in the same form as the IMP, and identical in appearance.

Trial Locations (28)

Unknown

Birmingham Heartlands Hospital, Birmingham

Birmingham Women's Hospital, Birmingham

Southmead Hospital, Bristol

St Michael's Hospital, Bristol

Burnley General Hospital, Burnley

University Hospital Coventry, Coventry

Royal Infirmary of Edinburgh, Edinburgh

Epsom Hospital, Epsom

St Helier Hospital, Epsom

Glasgow Royal Infirmary, Glasgow

Queen Elizabeth University Hospital, Glasgow

Liverpool Women's Hospital, Liverpool

Chelsea and Westminster Hospital, London

Kings College Hospital, London

Newham University Hospital, London

Royal London Hospital, London

St Thomas' Hospital, London

University College Hospital London, London

West Middlesex Hospital, London

Whipps Cross University Hospital, London

Royal Victoria Infirmary, Newcastle

Queen's Medical Centre, Nottingham

Queen Alexandra Hospital, Portsmouth

Princess Anne Hospital, Southampton

Sunderland Royal Hospital, Sunderland

Princess of Wales Hospital, Swansea

Singleton Hospital, Swansea

Princess Royal Hospital, Telford

All Listed Sponsors
collaborator

Birmingham Women's NHS Foundation Trust

OTHER_GOV

collaborator

Royal Infirmary of Edinburgh

OTHER

collaborator

Royal Victoria Infirmary

OTHER

collaborator

City Hospitals Sunderland NHS Foundation Trust

OTHER

collaborator

Liverpool Women's NHS Foundation Trust

OTHER

collaborator

The Leeds Teaching Hospitals NHS Trust

OTHER

collaborator

Barts & The London NHS Trust

OTHER

collaborator

Queen's Medical Center

OTHER

collaborator

Heart of England NHS Trust

OTHER

collaborator

University Hospitals Coventry and Warwickshire NHS Trust

OTHER

collaborator

Oxford University Hospitals NHS Trust

OTHER

collaborator

St Mary's Hospital, London

OTHER

collaborator

University College London Hospitals

OTHER

collaborator

University Hospital Southampton NHS Foundation Trust

OTHER

collaborator

King's College Hospital NHS Trust

OTHER

collaborator

University of Edinburgh

OTHER

collaborator

University of Nottingham

OTHER

collaborator

Queen Mary University of London

OTHER

collaborator

University of Warwick

OTHER

collaborator

University of Southampton

OTHER

lead

University of Birmingham

OTHER

NCT03065660 - Mifepristone and Misoprostol Versus Misoprostol Alone in the Medical Management of Missed Miscarriage | Biotech Hunter | Biotech Hunter