Dexamethasone Versus Dexmedetomidine

PHASE4CompletedINTERVENTIONAL
Enrollment

54

Participants

Timeline

Start Date

March 8, 2017

Primary Completion Date

April 28, 2018

Study Completion Date

April 30, 2018

Conditions
Postoperative Pain
Interventions
DRUG

dexamethasone 8 mg

At the level of the umbilicus, the high-frequency ultrasound linear array probe (L 4 - 12) will be placed transversely on the anterolateral abdominal wall between the subcostal margin and the iliac crest. localization of the fascial plane between the internal oblique and the transversus abdominis muscles will be done. The local anesthetic solution mixture will be injected with short bevel needle. The TAP block will be performed on the both side using the same technique and the same local anesthetic solution mixture volume. For the patients randomized to dexamethasone group, the local anesthetic solution mixture will consist of a total volume of 40 ml containing bupivacaine 0.25 % and dexamethasone 8 mg.

DRUG

dexmedetomidine 80 µg

At the level of the umbilicus, the high-frequency ultrasound linear array probe (L 4 - 12) will be placed transversely on the anterolateral abdominal wall between the subcostal margin and the iliac crest. localization of the fascial plane between the internal oblique and the transversus abdominis muscles will be done. The local anesthetic solution mixture will be injected with short bevel needle. The TAP block will be performed on the both sides using the same technique and the same local anesthetic solution mixture volume. For the patients randomized to dexmedetomidine group, the local anesthetic solution mixture will consist of a total volume of 40 ml containing bupivacaine 0.25 % and dexmedetomidine 80 µg.

DRUG

Bupivacaine 0.25% Injectable Solution

38 ml of the solution will be prepared to be used in transversus abdominis plane block

Trial Locations (1)

63514

Fayoum University hospital, El Fayoum Qesm

All Listed Sponsors
lead

Fayoum University Hospital

OTHER

NCT03064633 - Dexamethasone Versus Dexmedetomidine | Biotech Hunter | Biotech Hunter