Targeted Enteral Nutrient Delivery: A Prospective Randomized Study

NACompletedINTERVENTIONAL
Enrollment

19

Participants

Timeline

Start Date

February 22, 2017

Primary Completion Date

June 20, 2018

Study Completion Date

June 20, 2018

Conditions
Diabetes Mellitus, Type 2
Interventions
DIETARY_SUPPLEMENT

Sucrose plus Whole Milk Powder in Enteric Coating

Single dose enteric coated sucrose plus whole milk powder will be consumed by mouth. Blood will be drawn at baseline and then at 15 minute intervals for 3 hours from ingestion for measurement of GLP-1, PYY, C-peptide, insulin and glucose.Visual analog score will be used to record satiety and adverse symptoms every 15 minutes.

DIETARY_SUPPLEMENT

Non coated Sucrose plus Whole Milk

Single dose sucrose plus whole milk powder with separate enteric coating materials will be consumed by mouth. Blood will be drawn at baseline and then at 15 minute intervals for 3 hours from ingestion for measurement of GLP-1, PYY, C-peptide, insulin and glucose.Visual analog score will be used to record satiety and adverse symptoms every 15 minutes.

DIETARY_SUPPLEMENT

Sucrose in Enteric Coating

Single dose enteric coated sucrose will be consumed by mouth. Blood will be drawn at baseline and then at 15 minute intervals for 3 hours from ingestion for measurement of GLP-1, PYY, C-peptide, insulin and glucose.Visual analog score will be used to record satiety and adverse symptoms every 15 minutes.

DIETARY_SUPPLEMENT

Sucrose with Separate Enteric Coating Materials

Single dose sucrose with separate enteric coating materials will be consumed by mouth. Blood will be drawn at baseline and then at 15 minute intervals for 3 hours from ingestion for measurement of GLP-1, PYY, C-peptide, insulin and glucose.Visual analog score will be used to record satiety and adverse symptoms every 15 minutes.

DIETARY_SUPPLEMENT

Whey Protein in Enteric Coating

Single dose enteric coated whey protein will be consumed by mouth. Blood will be drawn at baseline and then at 15 minute intervals for 3 hours from ingestion for measurement of GLP-1, PYY, C-peptide, insulin and glucose.Visual analog score will be used to record satiety and adverse symptoms every 15 minutes.

DIETARY_SUPPLEMENT

Whey Protein with Separate Enteric Coating Materials

Single dose whey protein with separate enteric coating materials will be consumed by mouth. Blood will be drawn at baseline and then at 15 minute intervals for 3 hours from ingestion for measurement of GLP-1, PYY, C-peptide, insulin and glucose.Visual analog score will be used to record satiety and adverse symptoms every 15 minutes.

DIETARY_SUPPLEMENT

Pea Protein in Enteric Coating

Single dose enteric coated pea protein will be consumed by mouth. Blood will be drawn at baseline and then at 15 minute intervals for 3 hours from ingestion for measurement of GLP-1, PYY, C-peptide, insulin and glucose.Visual analog score will be used to record satiety and adverse symptoms every 15 minutes.

DIETARY_SUPPLEMENT

Pea Protein with Separate Enteric Coating Materials

Single dose pea protein with separate enteric coating materials will be consumed by mouth. Blood will be drawn at baseline and then at 15 minute intervals for 3 hours from ingestion for measurement of GLP-1, PYY, C-peptide, insulin and glucose.Visual analog score will be used to record satiety and adverse symptoms every 15 minutes.

Trial Locations (1)

90033

USC Diabetes & Obesity Research Institute (DORI), Los Angeles

All Listed Sponsors
lead

University of Southern California

OTHER

NCT03064347 - Targeted Enteral Nutrient Delivery: A Prospective Randomized Study | Biotech Hunter | Biotech Hunter