Two Doses of Multimeric-001 (M-001) Followed by Influenza Vaccine

PHASE2CompletedINTERVENTIONAL
Enrollment

120

Participants

Timeline

Start Date

April 9, 2018

Primary Completion Date

January 14, 2019

Study Completion Date

January 14, 2019

Conditions
InfluenzaInfluenza Immunisation
Interventions
BIOLOGICAL

Influenza Multimeric-001 Vaccine

The M-001 vaccine consists of 3 repetitions of 9 conserved linear epitopes that are prepared as a single recombinant protein. The M-001 vaccine is expected to protect against existing as well as future seasonal and pandemic virus strains.

OTHER

Placebo

Placebo is saline injection

BIOLOGICAL

Quadrivalent Recombinant Seasonal Influenza Vaccine

Quadrivalent Inactivated Influenza Vaccine (IIV4) for intramuscular injection is indicated for active immunization against influenza disease caused by influenza virus subtypes A and type B present in the vaccine.

Trial Locations (3)

52242-2600

University of Iowa - Vaccine Research and Education Unit, Iowa City

45229-3039

Cincinnati Children's Hospital Medical Center - Infectious Diseases, Cincinnati

77030-3411

Baylor College of Medicine - Molecular Virology and Microbiology, Houston

All Listed Sponsors
lead

National Institute of Allergy and Infectious Diseases (NIAID)

NIH

NCT03058692 - Two Doses of Multimeric-001 (M-001) Followed by Influenza Vaccine | Biotech Hunter | Biotech Hunter