NCT03054857View on ClinicalTrials.gov

The Effect of Dexmedetomidine Infusion on Post-operative Cognitive Function and Oxidative Stress in Cardiac Surgery

PHASE4CompletedINTERVENTIONAL
Enrollment

100

Participants

Timeline

Start Date

June 30, 2015

Primary Completion Date

December 31, 2016

Study Completion Date

December 31, 2016

Conditions
Oxidative StressCognition Disorders
Interventions
DRUG

Dexmedetomidine

After skin incision, the dexmedetomidine group received a loading dose of 0.5 mcg/kg of Dexmedetomidine in 20 minutes followed by a continuous IV infusion at 0.4 mcg/kg/hr until the end of operation.

DRUG

Placebo

The control group received a loading dose and continuous IV infusion of normal saline at the same volume and rate as in the dexmedetomidine group

All Listed Sponsors
lead

Chulalongkorn University

OTHER

NCT03054857 - The Effect of Dexmedetomidine Infusion on Post-operative Cognitive Function and Oxidative Stress in Cardiac Surgery | Biotech Hunter | Biotech Hunter