The Effect of General Anesthesia on Pharmacokinetics of Oxycodone in Pediatric

PHASE4RecruitingINTERVENTIONAL
Enrollment

40

Participants

Timeline

Start Date

July 8, 2019

Primary Completion Date

June 30, 2026

Study Completion Date

December 31, 2026

Conditions
Liquid Oxycodone
Interventions
DRUG

liquid oxycodone

"The group will include 25 patients (children 2-5 years old). In this group the children will be randomized to receive 0.1mg/kg of liquid oxycodone via an orogastric tube before the procedure at the beginning of general anesthesia (after intubation).~In this group 25 children will be randomized to receive 0.1mg/kg of liquid oxycodone via an orogastric tube after the procedure at the end of general anesthesia (before extubation).~The group will include 25 patients (children 6-8 years old). In this group the children will be randomize to receive 0.1 mg/kg of liquid oxycodone orally before the surgery in pre-op holding.~The group will include 25 patients (children 6-8 years old). In this group the children will be randomize to receive 0.1 mg/kg of liquid oxycodone orally after surgery in the Post Anesthesia Care Unit (PACU)."

Trial Locations (1)

02115

RECRUITING

Boston Children Hospital, Boston

All Listed Sponsors
lead

Boston Children's Hospital

OTHER