CAR T Cells in Mesothelin Expressing Cancers

PHASE1CompletedINTERVENTIONAL
Enrollment

65

Participants

Timeline

Start Date

April 6, 2017

Primary Completion Date

November 9, 2023

Study Completion Date

July 30, 2024

Conditions
Lung AdenocarcinomaOvarian CancerPeritoneal CarcinomaFallopian Tube CancerMesotheliomas PleuralMesothelioma Peritoneum
Interventions
BIOLOGICAL

huCART-meso cells

Intravenous administration or local delivery of lentiviral transduced huCART-meso cells in 7 cohorts with or without lymphodepletion..

Trial Locations (1)

19104

University of Pennsylvania, Philadelphia

All Listed Sponsors
collaborator

National Institutes of Health (NIH)

NIH

collaborator

Tmunity Therapeutics, a wholly owned subsidiary of Kite Pharma (a Gilead company)

UNKNOWN

lead

University of Pennsylvania

OTHER

NCT03054298 - CAR T Cells in Mesothelin Expressing Cancers | Biotech Hunter | Biotech Hunter