Benzodiazepine-free Anesthetic for Reduction of Delirium (B-Free)

PHASE1CompletedINTERVENTIONAL
Enrollment

480

Participants

Timeline

Start Date

April 1, 2017

Primary Completion Date

September 30, 2018

Study Completion Date

September 30, 2018

Conditions
Post-operative Delirium
Interventions
DRUG

Benzodiazepine - limited use strategy

"1. No routine use of any intraoperative benzodiazepines.~2. Accepted benzodiazepine use in the case of seizure, alcohol withdrawal, or known benzodiazepine dependence.~3. Accepted benzodiazepine use in patients who are hemodynamically unstable and/or have cardiac anatomy that puts them at high risk of developing ischemia on induction of anesthesia."

DRUG

Benzodiazepine - Ad libitum strategy

"1. Administration of some benzodiazepine to most patients undergoing cardiac surgery.~2. Accepted lack of benzodiazepine use in patients who have contraindications to the administration of these medications (e.g. documented allergy)."

Trial Locations (2)

Unknown

St. Boniface Hospital, Winnipeg

L8L 2X2

Dr Summer Syed, Hamilton

All Listed Sponsors
collaborator

Hamilton Health Sciences Corporation

OTHER

lead

McMaster University

OTHER

NCT03053869 - Benzodiazepine-free Anesthetic for Reduction of Delirium (B-Free) | Biotech Hunter | Biotech Hunter