Comparison of TAK-438 (Vonoprazan) to Lansoprazole in the Treatment of Gastric Ulcer Participants With or Without Helicobacter Pylori Infection

PHASE3CompletedINTERVENTIONAL
Enrollment

234

Participants

Timeline

Start Date

April 17, 2017

Primary Completion Date

February 19, 2020

Study Completion Date

May 26, 2020

Conditions
Gastric Ulcer
Interventions
DRUG

TAK-438

TAK-438 tablets

DRUG

Lansoprazole

Lansoprazole capsules

DRUG

TAK-438 Placebo

TAK-438 placebo-matching tablets

DRUG

Lansoprazole Placebo

Lansoprazole placebo-matching capsules

DRUG

Bismuth-Containing Quadruple Therapy

1 g Amoxicillin, 500 mg clarithromycin and 600 mg bismuth potassium citrate/bismuth tripotassium dicitrate, twice daily (BID).

Trial Locations (81)

100

National Taiwan University Hospital, Taipei

333

Chang Gung Memorial Hospital, Linkou, Taoyuan

1000

Philippine General Hospital, Manila

1634

St. Luke's Medical Center Global City, City of Taguig

4114

De La Salle University Medical Center, Dasmarinas City, Cavite

5000

West Visayas State University Medical Center, Iloilo City

6000

Cebu Doctors University Hospital, Cebu City

8000

Davao Doctors Hospital, Davao City

11217

Taipei Veterans General Hospital, Taipei

11490

Tri-Service General Hospital, Taipei

11923

Hanyang Univerisy Guri Hospital, Guri-si

13620

Seoul National University Bundang Hospital, Seongnam-si

14647

The Catholic University of Korea, Bucheon St. Mary s Hospital, Bucheon-si

15355

Korea University Ansan Hospital, Ansan-si

16247

The Catholic University of Korea, St. Vincent's Hospital, Suwon

21431

The Catholic University of Korea, Incheon St. Mary's Hospital, Incheon

21565

Gachon University Gil Medical Center, Incheon

26426

Yonsei University Wonju Severance Christian Hospital, Wŏnju

40010

The Second Affiliated Hospital of Chongqing Medical University, Chongqing

40447

China Medical University Hospital, Taichung

41944

Kyungpook National University Hospital, Daegu

42415

Yeungnam University Hospital, Daegu

49201

Dong-A University Hospital, Busan

54538

Wonkwang University Hospital, Iksan-si

54907

Chonbuk National University Hospital, Jeonju

61469

Chonnam National University Hospital, Gwangju

100020

Beijing Chao Yang Hospital, Beijing

100034

Peking University First Hospital, Beijing,P.R.

100039

The General Hospital of People's Armed Police Forces China, Beijing

100049

The Central Hospital of China Aerospace Corporation, Beijing

100050

Beijing Friendship Hospital, Capital Medical University, Beijing

100730

Beijing Tong Ren Hospital, Capital Medical University, Beijing

110016

General Hospital of Shenyang Military Region, Shenyang

130000

The First Hospital of Jilin University, Changchun

130012

Jilin 4th People'S hospital, Changchun

130033

China-Japan Union Hospital of Jilin University, Changchun

132011

Jilin central Hospital, Jilin

136000

Jilin Siping Central Hospital, Siping

200020

Ruijin Hospital, Shanghai Jiaotong Uni. School of Med., Huangpu Qu

200032

Zhongshan Hospital Fudan University, Shanghai

200092

Xinhua Hospital Affiliated to Shanghai Jiao Tong University School of Medicine, Shanghai

200442

Shanghai Tongji Hospital, Shanghai

210012

Nanjing First Hospital, Nanjing

212001

Affiliated Hospital of Jiangsu University, Zhenjiang

213003

The First People's Hospital of Changzhou, Changzhou

214062

Wuxi 4th People's Hospital, Wuxi

230024

The First Affiliated Hospital of Anhui Medical University, Hefei

241001

Yijishan hospital of Wan nan Medical college, Wuhu

241023

Wuxi People's Hospital, Wuxi

300052

Tianjin Medical University Affiliated General Hospital, Tianjin

310003

1st Affiliated Hospital of Zhejiang University, Hangzhou

310009

The Second Affiliated Hospital Zhejiang University School of Medicine, Hangzhou

310013

Zhejiang Hospital, Hangzhou

310016

Sir Run Run Shaw Hospital, Zhejiang University, School of Medicine, Hangzhou

325027

The Second Affiliated Hospital of Wenzhou Medical College, Wenzhou

330006

The First Affiliated Hospital of NanChang University, Nanchang

330009

Jiangxi Nanchang 3rd Hospital, Nanchang

337055

Jiangxi Pingxiang People's Hospital, Pingxiang

350025

Fuzhou General Hospital of Nanjing Military Area Command of Chinese PLA, Fuzhou

361003

The First Affiliated Hospital of Xiamen University, Xiamen

363000

Zhangzhou Hospital, Zhangzhou

410011

The 2nd Xiangya Hospital Central South University, Changsha

410018

Changsha Central Hospital, Yuhua

420104

Union Hospital of Tongji Medical College of Huazhong Science and Techology University, Wuhan

430030

Tongji Hospital, Tongji Medical College, Huazhong University of Science & Technology, Wuhan

430070

Wuhan General Hospital of Guangzhou Military, Wuhan

432000

Chenzhou No.1 People's Hospital, Chenzhou

434020

Jingzhou Central Hospital, Jingzhou

442000

Shiyan Taihe Hospital, Shiyan

510080

Guangdong General Hospital, Guangzhou

510655

The Sixth Affiliated Hospital of Sun Yat-Sen University, Guangzhou

518000

Peking University Shenzhen Hospital, Shenzhen

528000

The First People's Hospital of Foshan, Foshan

570208

Haikou People's Hospital, Haikou

650032

The First Affiliated Hospital of Kunming Medical College, Kunming

710004

The 2nd Hospital of Xi An Jiaotong University, Xi'an

750004

General Hospital of Ningxia Medical University, Yinchuan

810007

People's Hospital of Qinghai Province, Xining

02841

Korea University Anam Hospital, Seoul

03181

Kangbuk Samsung Hospital, Seoul

03722

Severance Hospital, Yonsei University, Seoul

Sponsors

Lead Sponsor

All Listed Sponsors
lead

Takeda

INDUSTRY