Transporters for Organic Cations and Glycemic Control in Patients With Neuropathic Pain.

PHASE4CompletedINTERVENTIONAL
Enrollment

29

Participants

Timeline

Start Date

November 1, 2015

Primary Completion Date

May 1, 2018

Study Completion Date

July 1, 2019

Conditions
Neuropathic PainType 2 Diabetes MellitusDiabetic Neuropathy, Painful
Interventions
PROCEDURE

Serial Blood Samples

Serial blood samples were collected at times 0, 0.5, 1, 1.5, 2, 2.5, 3, 4, 6, 8, 10, 12, 24 and 36 hours after gabapentin administration, for all patients.

PROCEDURE

Serial Urine Samples

Serial urine samples were collected at intervals 0-8 hours, 8-16 hours, 16-24 hours and 24-36 hours after gabapentin administration, for all patients.

DRUG

Gabapentin 300 mg

All patients were treated with oral single dose of gabapentin 300 mg.

DRUG

Cetirizine Hydrochloride 10 mg

Patients of control group were treated with cetirizine hydrochloride, 10 mg, twice as day, orally, for five days.

All Listed Sponsors
collaborator

University of Sao Paulo

OTHER

lead

Natalia Valadares de Moraes

OTHER

NCT03047278 - Transporters for Organic Cations and Glycemic Control in Patients With Neuropathic Pain. | Biotech Hunter | Biotech Hunter