The Regulation of Human Skeletal Muscle Mass by Contractile Perturbation

NACompletedINTERVENTIONAL
Enrollment

14

Participants

Timeline

Start Date

May 1, 2017

Primary Completion Date

May 1, 2018

Study Completion Date

September 1, 2018

Conditions
Muscle AtrophyDisuse Atrophy (Muscle) of Lower Leg
Interventions
OTHER

Unilateral Resistance Exercise

Unilateral Resistance exercise will include training three days per week and each session will include 3 sets of leg extension and 3 sets of leg press. In each set, the participant will complete a maximum of 12 repetitions.

PROCEDURE

Immobilization

During the last two weeks of the study (week 8-10), a Don Joy adjustable knee brace will be applied to the participant's leg randomized to immobilization. The brace will be applied at a 40 degree angle relative to complete extension.

Trial Locations (1)

L8S 4K1

Exercise Metabolism Research Laboratory, McMaster Univeristy, Hamilton

All Listed Sponsors
lead

McMaster University

OTHER

NCT03046095 - The Regulation of Human Skeletal Muscle Mass by Contractile Perturbation | Biotech Hunter | Biotech Hunter