Cervical Preparation of Abortions Under Paracervical Block in the First Trimester:

NACompletedINTERVENTIONAL
Enrollment

110

Participants

Timeline

Start Date

June 1, 2017

Primary Completion Date

March 13, 2019

Study Completion Date

November 15, 2022

Conditions
Surgical Abortion
Interventions
DRUG

Mifépristone versus Misoprostol

The women will be randomized into two groups: Mifépristone group and Misoprostol group. The main endpoint will be the per-operating pain. The other endpoints are the pre and post-operative pain, the complications (cervical tearing, uterine perforation, hemorrhage requiring the use of blood products or an hemostatic intervention), the surgical time necessary to terminate the pregnancy, the side-effects of the drugs. The amount of per-operating bleeding and the duration of the intervention . The investigators assume that the use of Mifepristone in the cervical preparation of the surgical abortion under LA would reduce the per-operating pain. The number of patients required is 55 in each arm.

Trial Locations (1)

Unknown

Hôpital de la conception Assistance Publique Hôpitaux de Marseille, Marseille

All Listed Sponsors
lead

Assistance Publique Hopitaux De Marseille

OTHER

NCT03043014 - Cervical Preparation of Abortions Under Paracervical Block in the First Trimester: | Biotech Hunter | Biotech Hunter