Study to Evaluate Faricimab (RO6867461; RG7716) for Extended Durability in the Treatment of Neovascular Age Related Macular Degeneration

PHASE2CompletedINTERVENTIONAL
Enrollment

76

Participants

Timeline

Start Date

January 27, 2017

Primary Completion Date

January 11, 2018

Study Completion Date

March 29, 2018

Conditions
Neovascularization, ChoroidalMacular Degeneration, Age-Related
Interventions
DRUG

Faricimab

Faricimab was administered via IVT injections as specified during the treatment period.

DRUG

Ranibizumab

Ranibizumab was administered via IVT injections as specified during the treatment period.

DRUG

Sham Procedure

The sham was a procedure that mimicked an IVT injection and involved the blunt end of an empty syringe (without a needle) being pressed against the anesthetized eye. It was administered to participants in the faricimab treatments arms at applicable visits to maintain masking among treatment arms.

Trial Locations (25)

11021

Vitreoretinal Consultants, Great Neck

21209

The Retina Care Center, Baltimore

30909

Southeast Retina Center, Augusta

32308

Southern Vitreoretinal Assoc, Tallahassee

32901

Florida Eye Associates, Melbourne

33064

Rand Eye, Deerfield Beach

33711

Retina Vitreous Assoc of FL, St. Petersburg

38138

Charles Retina Institute, Germantown

46290

Midwest Eye Institute, Indianapolis

50266

Wolfe Eye Clinic, West Des Moines

55435

Vitreo Retinal Surgery, Minneapolis

76012

Texas Retina Associates, Arlington

76087

Strategic Clinical Research Group, LLC, Willow Park

78750

Retina Research Center, Austin

79606

Retina Res Institute of Texas, Abilene

84107

Retina Associates of Utah, Salt Lake City

85053

Retinal Consultants of Arizona, Phoenix

85704

Retina Associates Southwest PC, Tucson

87109

Eye Associates of New Mexico, Albuquerque

89502

Sierra Eye Associates, Reno

93309

California Retina Consultants, Bakersfield

95008

Retinal Diagnostic Center, Campbell

97221

Retina Northwest, Portland

97401

Oregon Retina, LLP, Eugene

80909-1183

Retina Consultants of Southern Colorado PC; Clinical Research Department, Colorado Springs

All Listed Sponsors
lead

Hoffmann-La Roche

INDUSTRY

NCT03038880 - Study to Evaluate Faricimab (RO6867461; RG7716) for Extended Durability in the Treatment of Neovascular Age Related Macular Degeneration | Biotech Hunter | Biotech Hunter