NCT03032783View on ClinicalTrials.gov

A Two Step Approach to Allogeneic Hematopoietic Stem Cell Transplantation for Patients With Hematologic Malignancies-Increasing GVT Effects Without Increasing Toxicity

PHASE2Active, not recruitingINTERVENTIONAL
Enrollment

51

Participants

Timeline

Start Date

January 31, 2017

Primary Completion Date

December 2, 2025

Study Completion Date

December 2, 2025

Conditions
Hematopoietic and Lymphoid Cell Neoplasm
Interventions
RADIATION

Total-Body Irradiation

Undergo Total Body Irradiation

PROCEDURE

Donor Lymphocyte Infusion

Undergo Donor Lymphocyte Infusion

DRUG

Cyclophosphamide

Given IV

DRUG

Tacrolimus

Given IV

DRUG

Mycophenolate Mofetil

Given IV

PROCEDURE

Allogeneic Hematopoietic Stem Cell Transplantation

Undergo Hematopoietic Stem Cell Transplantation

Trial Locations (1)

19107

Sidney Kimmel Comprehensive Cancer Center at Thomas Jefferson University, Philadephia

All Listed Sponsors
lead

Sidney Kimmel Cancer Center at Thomas Jefferson University

OTHER