102
Participants
Start Date
January 26, 2017
Primary Completion Date
March 21, 2018
Study Completion Date
October 18, 2022
Oral Glucose Tolerance Test (OGTT)
Once we test the fasting plasma glucose (after an overnight fast), subject will receive a 75g glucose beverage they will have to drink within 5 minutes. Then after drinking the beverage, 8 blood samples will be collected through the IV catheter, over the next 3 hours.
Assessment of dietary compliance
Assessment of consumption of non-caloric artificial sweeteners
Stool sampling
Subjects will provide a stool sample.
Sodium Saccharin
Subjects in group 1 and group 3 will be provided with sodium saccharin.
Placebo
Subjects in group 2 will be provided with placebo.
Lactisole
Subjects in group 3 and group 4 will be provided with lactisole.
Translational Research Institute for Metabolism and Diabetes, Orlando
AdventHealth Translational Research Institute
OTHER