Choline Supplementation During Pregnancy: Impact on Attention and Social Withdrawal

PHASE1Active, not recruitingINTERVENTIONAL
Enrollment

600

Participants

Timeline

Start Date

June 12, 2017

Primary Completion Date

December 31, 2026

Study Completion Date

December 31, 2026

Conditions
Child DevelopmentPrenatal Stress
Interventions
DRUG

Choline

Mothers are instructed to take the capsules twice a day, five 450 mg phosphatidylcholine capsules at breakfast and five phosphatidylcholine 450 mg capsules at dinner. Increased awareness into the benefits of choline by obstetricians and pregnant women, as well as our recently published results from an observational study showing a wide distribution of serum choline concentrations in pregnant women, suggest that serum choline concentration is a more apt independent variable for analyses.

DRUG

Placebo

Mothers are instructed to take the capsules twice a day, five placebo corn oil capsules at breakfast and five placebo corn oil capsules at dinner. Increased awareness into the benefits of choline by obstetricians and pregnant women, as well as our recently published results from an observational study showing a wide distribution of serum choline concentrations in pregnant women, suggest that serum choline concentration is a more apt independent variable for analyses.

Trial Locations (2)

80045

UCHealth, Aurora

80218

Saint Joseph Hospital, Denver

All Listed Sponsors
lead

University of Colorado, Denver

OTHER