Adjacent Segment Mechanics in Cervical Arthrodesis Patients

CompletedOBSERVATIONAL
Enrollment

106

Participants

Timeline

Start Date

April 30, 2016

Primary Completion Date

December 30, 2024

Study Completion Date

December 30, 2024

Conditions
Intervertebral Disc Degeneration
Interventions
PROCEDURE

C5-C6 arthrodesis

A standard Smith Robinson anterior medial approach to the cervical spine. Vertebral endplates will be prepared by removing the cartilage endplate. Tricortical anterior iliac crest autografts will be harvested with a low-speed oscillating saw. Allografts will be fresh-frozen, vacuum-sealed, nonradiated tricortical grafts. All grafts will be fashioned in a typical Smith-Robinson formation. The motion segment will be distracted approximately 2-mm beyond the graft height before the insertion of each graft. Fusion plate will be contoured to cervical lordosis. Cervical plates will be positioned using surgical midline markers. All rigid anterior plate fixations will be performed using titanium anterior fixed-angle screw systems.

Trial Locations (1)

15203

University of Pittsburgh Biodynamics Lab, Pittsburgh

All Listed Sponsors
lead

University of Pittsburgh

OTHER

NCT03028402 - Adjacent Segment Mechanics in Cervical Arthrodesis Patients | Biotech Hunter | Biotech Hunter