294
Participants
Start Date
January 31, 2017
Primary Completion Date
March 31, 2019
Study Completion Date
March 31, 2019
Physical activity
Physical activity+ MED diet
Physical activity+green MED diet
\*\*\*\*Sub-study from all 3 main arms: Autologous fecal microbiota supplement intervention derived from the time of maximal weight loss: At the 6-month time period, the time of anticipated greatest weight reduction, participants's feces samples will be processed to capsulized inocula. Samples will be frozen within 2 hours and will be kept at -80c pending analysis. Participants will be randomized to receive either research capsules or identical placebo capsules between 8 and 14 months time period. Placebo capsules will consist of a combination of powdered cocoa and vegetable gelatin in normal saline/glycerol and will be identical in appearance to research capsules.
Nuclear research center Negev, Dimona
Harvard School of Public Health (HSPH)
OTHER
University of Leipzig
OTHER
Ben-Gurion University of the Negev
OTHER